Two brothers from Leicester are believed to have traveled to Syria and joined ISIS as part of a second large group of medical students studying in Sudan.
Ibrahim and Mohamed Ageed are thought to have left Khartoum along with as many as five other British nationals and two students from Canada and America, where they were studying at the private medical school.
Flying out last Friday, the group traveled to Turkey and thought to be heading for Syria.
The Ageed brothers were in their final year at the privately-owned University of Medical Sciences and Technology (UMST), where they were expected to attend their final exams this week.
Ibrahim's father, Adil, has reportedly flown to Turkey to try and prevent his sons from joining ISIS.
The news comes after the identities of nine British medical students were revealed as having traveled to join ISIS last March.
In total, at least 16 British Sudanese medical students have left the medical school and joined ISIS in the last four months.
Ibrahim and Mohamed, aged 21 and 23, grew up in Oadby, Leicester, with parents Adil Ageed, a doctor, and Nawal Salih.
Like a several of the parents from the group who joined ISIS in March, Mr Ageed is thought to have flown to Turkey in a bid to track down his sons and prevent them crossing the border.
Their mother was said to be 'very worried and very upset' because her sons had suddenly left in the middle of taking their exams - and 'didn't understand' their actions.
The brothers' social media profiles bears the usual reflections of two young men, who enjoy football, bands such as Coldplay, computer games and TV shows such as The Inbetweeners and Game of Thrones.
Less than three weeks ago, Manchester United fan Mohamed retweeted a post by new signing Memphis Depay saying he was 'proud to be a Red'
The news has come as a shock to the Oadby community, where the brothers grew up.
Neighbour Roger Edwards said: 'It is a shock to hear it is happening. They have been here about five years and are very polite, great neighbours.'
Another, who asked not to be named, said described one of the brothers as a 'a very nice gentleman.'
Dr Ahmed Babikir, a dean at UMST, said: 'We confirmed reports from multiple parties that 12 medical students at the university left for Turkey on Friday.
'Logic says that they travelled to join the Daesh organisation (ISIS).' The dean added that three of students were women.
A Foreign Office spokeswoman confirmed that seven British nationals have travelled to Turkey from Sudan. She said: 'We are working closely with the Turkish authorities to establish their whereabouts and provide consular assistance.'
The news comes two weeks after ISIS released a propaganda video featuring a British doctor, urging Muslims in Sudan and England to join ISIS.
With his strong British accent he is believed to be Ahmed Sami Khader, one of nine British medical students who had been studying in Sudan before flying to Istanbul - and then sneaking into Syria in March.
Appearing under the nom de guerre Abu Amir al-Muhajir, the doctor is clean shaven and speaks in flawless English about the different medical facilities.
Credit: Daily mail
